منابع مشابه
Microbial hydroxylation of sclareol by Rhizopus stolonifer.
Incubation of sclareol with Rhizopus stolonifer affords in high yield a mixture of triols with 18-hydroxy-sclareol as the main component.
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Mycobacterium smegmatis PTCC 1307 (CIP 73.26) was used as a microbial agent to produce androsta-1,4-diene-3,17-dione (ADD) and androst-4-ene-3,17-dione, two useful precursors in the synthesis of steroid drugs. The side chain of cholesterol, as the substrate, was selectively cleaved in the presence of five enzyme inhibitors. An intermediate structure with intact side chain, cholest-4-ene-3-one, ...
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Screening scale studies were performed to biotransform anthelmintic drug albendazole by using twelve bacterial strains representing six genera and five actinomycetes cultures. Among the cultures studied, Bacillus subtilis MTCC 619, Escherichia coli MTCC 118 and Klebsiella pneumoniae MTCC 109 could transform albendazole to one metabolite whereas, Enterobacter aerogenes NCIM 2695, Klebsiella aero...
متن کاملMicrobial Transformation of (-)-Alloisolongifolene
(-)-Alloisolongifolene (1) is a structural analogue of the naturally occurring longifolene. The microbial transformation of (-)-alloisolongifolene (1) by Cunninghamella elegans afforded two new metabolites, 3a-hydroxyalloisolongifolol (2) and 13-hydroxyalloisolongifolol (3). The structures of the metabolites were deduced on the basis of their spectral data, including 1D and 2D NMR, IR and HREIMS.
متن کاملMicrobial transformation of validamycins.
Alpha- or beta-Glucosidic linkage of validamycin was selectively cleaved by microbial hydrolysis and especially the conversion of validamycin C into validamycin A by the selective hydrolysis of alpha-glucoside linkage has important significance because validamycin C is considerably less active than validamycin A. Semisyntheses of validamycins including a new validamycin, beta-D-galactosyl-vali...
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ژورنال
عنوان ژورنال: Agricultural and Biological Chemistry
سال: 1982
ISSN: 0002-1369,1881-1280
DOI: 10.1271/bbb1961.46.2477